90% of people given vaccine by Sinovac show promising results
Beijing Sinovac Biotech Ltd said its coronavirus shot is safe and capable of eliciting an immune response from human trials, suggesting the shot's potential in defending against infection of the coronavirus disease.
The Beijing-based company's vaccine, called CoronaVac, hasn't caused severe side effects and more than 90% of people administered with the shot on a 14-day interval have induced neutralising antibodies two weeks after inoculation, Sinovac said in a press release on Sunday.
The preliminary findings come from phase I and II trials in China. A total of 743 healthy people ages 18 to 59 either received shots on two schedules or a placebo. More data will be uncovered from another group in the trial that received shots on a 28-day interval. Sinovac plans to publish its results in academic journals, according to a company spokesperson.
Using a killed version of the coronavirus, Sinovac's vaccine is among five Chinese experimental shots that have reached the crucial final stage of human testing before they can be approved for public use.
The company announced a partnership this month with Instituto Butantan to conduct its phase III trial in Brazil, where the novel pathogen has caused the second-largest outbreak in a pandemic that so far infected more than 7.7 million people.
Since lockdowns and social-distancing measures have helped to keep infection rates low in many countries, some of the world's leading vaccine efforts are seeking to conduct phase III trial in active outbreaks to evaluate the effectiveness of their shots.
Authorities in Brazil have approved the vaccine co-developed by the University of Oxford and AstraZeneca Plc to carry out late stage trials there, while Cambridge, Massachusetts-based Moderna Inc is set to go into phase III trials in the US.
巴西还同意了由牛津大学（University of Oxford）和阿斯利康制药公司（AstraZeneca Plc）合作开发的疫苗在巴西进行后期试验。与此同时，剑桥大学（Cambridge）和马萨诸塞州的摩登那公司（Moderna Inc）也将在美国进行疫苗的三期试验。